Educational Case: Wilms Tumor

Adult Nephroblastoma (Wilms Tumor): A Case Report

Nephroblastoma (Wilms tumor) is the most common primary malignant renal tumor in children. Rarely, it may present in the adult age group. This is a case report of a diagnosed case of a 29-yearold female presenting with right-sided flank pain and hematuria. Abdominal sonogram revealed a right renal mass measuring 1.55 × 1.88 × 1.62 cm on the lower pole of the right kidney. CT scan showed a 2.1 ×...

MiR-21 Expression in Wilms’ Tumor

Background and Objective: Wilms’ tumor (WT) is the most common genitourinary tract tumor in children. MicroRNAs (miRNAs) are small non-coding RNAs; their role in the pathogenesis of many types of human cancers has been identified. We aimed to evaluate the expression of miR-21, a well-known oncomir, in WT tissue samples which is a very common urinary tract malignancy in children...

Wilms Tumor

[Wilms' tumor].

Today the prognosis in children with nephroblastoma is excellent. With the combination of surgery, chemotherapy and radiation more than 80% of children can be cured. Because of acute toxicity and late effects of treatment (scoliosis, cardiotoxicity, fertility problems and second malignancies) a major issue in the management of children with this kind of malignancy is the reduction of chemothera...

Kidney : Nephroblastoma ( Wilms tumor )

Other names: Nephroblastoma Note: Wilms' tumor, although generally rare, is the most common abdominal malignancy in children. Wilms' tumor cells are believed to derive from pluripotent embyronic renal precursor cells. Thus, Wilms' tumors are linked to the early development of the kidney. While most are isolated sporadic tumors, approximately 10% of cases are associated with genetic syndromes an...